Research
Lectures
Books
Blogs
Drug Safety
Dr. Bremner's home page
Emory Clinical Neuroscience Research Unit (ECNRU)
|
|
Head lice are a big problem, affecting 6 to 12 million people in the US every year. Head lice
are becoming endemic amongst our children. Unfortunately the pharmacological treatments for head lice
are not that great. Malathion (Ovide) is an organophosphate that kills lice by inhibiting the cholinesterase enzyme.
Malathion works well for lice, unfortunately it has the side effect of being highly flammable, so
little children should stay away from fires, to keep their heads from catching on fire.
The most commonly used prescribed medication for these problems is lindane (Kwell).
Doctors apparently have not figured out yet that it doesn’t work and has been associated
 :with some potential safety concerns. Efficacy of lindane has been decreasing over the past
few decades to lindane due to the emergence of treatment resistant lice. Lindane has limited efficacy,
killing only 17% of lice after a 3 hour period, and none after 10 minutes, the recommended time of exposure. \
In other words, take Lindane as directed, and it will do NOTHING!
|
|